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Calm Biotic 3 Billion - 30 Capsules Moon Phase Fuchsite also enhances connection withNatural Factors Calm Biotic is an innovative formula featuring Lactobacillus helveticus R0052 and Bifidobacterium longum R0175, two proprietary strains shown to help reduce feelings and symptoms of mild to moderate stress and promote a healthy mood balance. Both strains are resistant to gastric acid, making Calm Biotic a convenient, shelf stable, one per day capsule that contributes to a natural, healthy gut microbiome with no refrigeration required.